January loan signing De Jong is yet to open his goalscoring account on Tyneside, while Cisse has found the back of the net on only three occasions in all competitions to date this season.
By contrast, Remy has taken his tally for the campaign to 13 since his return from a three-match ban, and Pardew is keeping his fingers crossed that the France international's influence on and off the pitch can inspire his fellow frontmen.
He said: "Both of those guys need to score goals between now and the end of the year.
"They are both going to get chances and they are going to need to take them. That's the competition I need."
De Jong, 23, knows what he can do between now and the end of the season will determine whether or not the Magpies decide to try to make his temporary switch from Borussia Monchengladbach permanent during the summer.
Pardew said: "He needs to make a success of these last 10 games. He's had a good start.
"He came into a team that unfortunately had lost [Yohan] Cabaye and we lost a couple of games and there was no Remy - it was difficult for him.
"But he is finding his feet. Every day in training, he looks better and better, so hopefully he can have a big impact between now and the end."
Cisse, whose form has been largely indifferent since his first year in English football, has been repeatedly linked with a move away from Tyneside in recent months, and the club has a big decision to make on the 28-year-old Senegal international's future too.
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