The Potters will mark the occasion with a series of events before Sunday's clash against Tottenham at the Britannia Stadium, including a variety of on-field entertainment and a parade of more than 80 former players.
The likes of Sir Geoff Hurst and Gordon Banks are confirmed to appear in that group, and, while Pulis acknowledges how special it will be for supporters, he wants his side to focus on Spurs and nothing else.
"We're hoping we can put in a good performance. It's a big game for us as we celebrate the 150th anniversary of the football club," he said.
"The club has a lot of stuff going on around the game but what we have to do is concentrate on giving Tottenham a run for their money.
"The celebrations will be good for the crowd but we won't see any of it - we'll be preparing in the dressing room.
"The big thing for us is to concentrate on the game and let everyone else enjoy the occasion.
"The important thing for me is the 90 minutes. When the whistle goes the supporters will want the players to be right on it and taking the game to Tottenham."
- Sports & Recreation