The Derby frontman will partner Shane Long in attack with Keane having been ruled out of the game with a calf strain after a scan on Sunday.
Elsewhere, manager Giovanni Trapattoni will keep faith with the bulk of the side which started Friday night's 0-0 draw in Sweden with Glenn Whelan returning from an ankle injury in place of Paul Green.
Republic of Ireland team: David Forde; Seamus Coleman, John O'Shea (Capt), Ciaran Clark, Marc Wilson; Jon Walters, Glenn Whelan, James McCarthy, James McClean; Shane Long, Conor Sammon.
- Sports & Recreation
- Glenn Whelan
- Giovanni Trapattoni
- Shane Long