Vaughan returned after a seven-game absence as a substitute in last week's derby defeat to Leeds and is edging closer to his first start since October 23 after shaking off a thigh injury.
But fellow striker Jermaine Beckford remains doubtful due to the hamstring problem that has kept him sidelined since the win at Barnsley early last month.
Sean Scannell is pushing for a recall after missing the last four games with a hamstring injury of his own, while fellow striker Lee Novak and midfielder Oliver Norwood are hoping to feature after they were unused substitutes last week.
Defender Paul Dixon is expected to return to the squad after missing out altogether last week and winger Adam Hammill, on loan from Wolves, is pushing for his first start since early November.
Huddersfield are chasing their first league win in five matches.
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- Jermaine Beckford