Talbot was forced off with the injury early in the second half of the Spireites' 2-1 defeat at Wycombe on Saturday.
The versatile 26-year-old, an ever-present for the npower League Two club this season, was told the news after seeing a specialist on Tuesday afternoon.
"It's not a major injury but he should be out for four weeks," said Chesterfield physio Jamie Hewitt. "He can start running in a couple of weeks and then progress to ball work."
- Sports & Recreation