The England winger was forced off during Spurs' 2-1 Capital One Cup defeat to West Ham with a hamstring injury and will not be fit to play any part at St Mary's.
Caretaker manager Tim Sherwood will have captain Michael Dawson available after a ban but Paulinho is still suspended and defensive duo Younes Kaboul (thigh) and Jan Vertonghen (ankle) are also missing.
- Sports & Recreation
- Younes Kaboul
- Tim Sherwood