Boss Dean Smith will change an unbeaten line-up for the first time in six games to counter the loss of top scorer Will Grigg and goalkeeper Aaron McCarey.
Grigg, who has 19 goals to his name this season, is away on international duty with Northern Ireland although he is set to miss their World Cup qualifiers against Russia and Israel due to a hamstring problem.
McCarey was this week recalled from his loan spell at the Banks's Stadium by parent club Wolves, with highly-rated Manchester United stopper Sam Johnstone subsequently brought in on a deal until the end of the season.
Johnstone will now start at Victoria Park as the Saddlers aim to close the three-point gap on the play-off places.
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