The striker, 19, has been recalled from a loan spell at Staines Town where the Oxford youth product had netted nine times in 16 games as he helped steer the side away from relegation danger.
And after featuring in their 2-0 defeat to Dover on Tuesday night, Marsh, who scored his first senior goal for the club against Southend earlier this season, was recalled by manager Chris Wilder who ended speculation over his own future at the Kassam on Friday by signing a new 12-month deal.
Oxford ran out 3-0 winners against Rochdale last time out and will look to end an ultimately frustrating season with victory against Stanley. They were without captain Jake Wright in that match and the defender is a doubt for the trip.
Sean Rigg and Michael Raynes returned to the starting line-up against Dale and they will hope to keep their place, while James Constable staked his claim for a place in the XI after scoring following his introduction at half time.
Youngsters Callum O'Dowd and Sam Long are expected to be involved once more as the U's look towards the 2013/14 League Two campaign.
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- Staines Town