Wyke, 20, who spent three months on loan with Pools at the end of last year, making nine appearances without scoring, started in the club's last match - the home defeat to Preston on New Year's Day - and is expected to play some part this weekend.
Midfielder Simon Walton is hoping to shake off the hamstring strain that forced him out of the action against Preston, leaving manager John Hughes with a virtually full-strength squad to choose from.
Goalkeeper Andy Rafferty, who is continuing his rehabilitation following knee surgery during the summer, remains Hughes' only absentee.
Strikers Luke James and James Poole are pushing for recalls after stepping off the substitutes' bench in the second half against Preston, while Hughes must decide whether to recall midfielder Andy Monkhouse and teenage defender Jack Baldwin in pursuit of his side's third league win of the season.
- Sports & Recreation