The two Red Bull cars deployed divergent tactics at Buddh on a weekend when the soft tyres faded very quickly but the mediums had great longevity.
While Vettel qualified and started on softs, but shed them for mediums as early as lap two, Webber used mediums in his first and third stints, with just four laps on softs mid-race in between.
Vettel's route proved more successful as despite falling into the midfield following his lap-two stop, he was in front once Webber had made his last switch back to mediums.
Webber denied that he might have been better off sticking with medium tyres for most of the race before making a very late swap to softs.
"You've got to protect against a safety car as well," he said.
"You've got to run the softs for a few laps, which we did.
"If you put primes [mediums] on again [after the first stop], you're a little bit exposed to the safety car and it could get tricky."
The Australian ultimately retired with an alternator failure while running second.
"In the end I still have a smile on my face," he said. "I couldn't do any more today."
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