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While Germany have proved themselves serial winners — most recently being crowned world champions in 2014 — England’s sole trophy was earned back in 1966.
But Low believes they are on the right track under Southgate, following their semi-final at the last World Cup.
“Tomorrow is going to be a totally different situation, a totally different story,” said the Germany coach.
“The English side, we have to say, we have to admit they maybe weren’t so present at the top of world football. But in the near past, they have improved a lot.
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“Also under the leadership of Gareth Southgate — in 2018, for example. They have great individual qualities, they are a great team, they’re defending very well and in attack.
“Look at Harry Kane at the level that he plays. He can score goals out of every situation. These are his skills, his qualities. He has all of them. He is both footed, is very good in the air. He can protect the ball very well.
“Of course we have to be focused. But England have also Raheem Sterling, Phil Foden, Mason Mount maybe. So they have a lot of strong offensive players, attacking players with Jadon Sancho as well and Marcus Rashford. All these young talents, they’re so fast. They like to enter duels, so their attack is a real threat.”
But Neuer, who was part of the team that beat England 4-1 at the 2010 World Cup, says they are confident of victory.
“We are all looking forward to this classic situation in football — Germany against England in Wembley, this historic stadium,” he said. “It is something special for us. We are very motivated.
“It is difficult to say what they are thinking. We know about our qualities. We are confident and convinced we can beat the English.
“We know they are strong. They have a lot of weapons, on the wings especially. We have to show that belief like we’ve done before.
“We have conceded more goals but they have not scored many, so we need to be stable in defence, work hard and show our quality in attack on the pitch. That all talks in favour of our attacking game. We have great players in our ranks. We need to be patient.”
Germany have doubts over midfielder Ilkay Gundogan, centre-half Antonio Rudiger and wing-back Robin Gosens through illness and injury on Tuesday night.
Low said: “We decide with the doctors on match day. Maybe they will get up and feel well, but maybe it will get worse overnight, so we need to wait. I don’t know if these three will be at our disposal, but we will have other solutions.
“Ilkay suffered a cranial bruise. He felt a little bit better today, yesterday he still felt a little dizzy, especially in training, so we said we had to stop his load. Today he did a good job, so we will decide tomorrow.”
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