The couple will attend The One Young World Manchester Summit on September 5, where the Duchess of Sussex is a counsellor alongside Justin Trudeau and Jamie Oliver, before jetting off to Germany for the Invictus Games Düsseldorf One Year To Go ceremony the next day.
The Duke and Duchess will then return to the UK for the WellChild Awards 2022 in London on September 8.
The Duke and Duchess of Sussex: Prince Harry & Meghan Markle
It is unclear whether the couple will make time to visit the Queen.
It will be only the third time Meghan has returned to the UK in more than two years since the couple quit their royal roles in 2020 and moved to the US.
The couple introduced their daughter Lilibet to her great-grandmother during their last visit to the UK.
The Queen met with the Sussexes at the Platinum Jubilee celebrations, according to reports, but Harry and Meghan, who tried to maintain a low profile so as not to upstage the Queen, found the day “difficult”, a royal expert has since claimed.
The Duke and Duchess of Sussex with their children
The Royal Family appeared united, after the fallout of that bombshell Oprah interview, as they wished Meghan Markle a happy 41st birthday on their official social media channels, earlier this month.
It came after The Duke was embroiled in a legal row with the Government over a Home Office decision to strip him of his UK security with his lawyers saying he was “unable to return home” over fears it “was too dangerous”.
Meghan and Harry have established a new life for themselves in the celebrity enclave of Montecito in California, buying a multimillion-pound home and launching a non-profit foundation, after stepping down as working royals for financial freedom.
The couple have also signed lucrative deals – thought to be worth well over £100 million – with Spotify and Netflix which have given them the capital to pursue their new lifestyle and public goals.