Gonzalo Higuain's first return to Stadio San Paolo since leaving Napoli for Juventus saw the striker fail to record a single touch in the opposition penalty area.
Higuain joined Serie A champions Juventus in July 2016 and had scored in both of his previous appearances against his former side this season.
The Argentine received a predictably angry response from the Napoli faithful on his return to the club on Sunday and his goalless run extended to five games after an ineffective display.
Higuain mustered a single shot in the 90 minutes, with that solitary effort blocked, as Juventus moved six points clear of Roma following a 1-1 draw, with Marek Hamsik cancelling out Sami Khedira's sixth-minute opener in a tight match.
The 29-year-old striker will have an immediate opportunity to have a more impactful match at Stadio San Paolo as Juventus will return to Napoli on Wednesday for the second leg of their Coppa Italia semi-final, with Massimiliano Allegri's men leading 3-1.