Jack Sparkes and Abu Kamara are both named in the starting XI, replacing Anthony Scully and Alex Robertson.

Scully isn’t included in Mousinho’s match-day 18, while Robertson is among the substitutes.

It means Sparkes and Kamara, who both lined-up for Pompey in their EFL Trophy clash with Fulham Under-21s on Tuesday night, come in against fifth-placed Boro.

For Sparkes, who will operate on the left wing, it represents a full league debut for the Blues.

Pompey continue to be without injured pair Kusini Yengi and Tom Lowery.

Pompey: Norris, Rafferty, Poole, Shaughnessy, Ogilvie, Pack, Morrell, Kamara, Whyte, Bishop, Sparkes.

Subs: Schofield, Swanson, Robertson, Saydee, Raggett, Devlin, Lane.