Team captains LeBron James and Giannis Antetokounmpo both exited the All-Star Game in Utah on Sunday due to injuries.

Los Angeles Lakers forward James appeared to hurt his hand attempting to block a Pascal Siakam shot in the second quarter and was ruled out for the second half.

James finished the game with 13 points on 54.5 per cent field goal shooting with four assists in 14 minutes.

The four-time NBA MVP's exit meant both Team LeBron and Team Giannis would be without their captains for the second half.

Milwaukee Bucks forward Antetokounmpo withdrew from the All-Star Game early with a pre-existing wrist injury, scoring two points before stepping out inside a minute.

James, who missed three games last week due to an ankle injury, is averaging 30.0 points, 8.4 rebounds and 7.0 assists for the Lakers this season.

Antetokounmpo is averaging 31.8 points, 12.2 rebounds and 5.4 assists for the Bucks, who are second in the Eastern Conference with a 41-17 record.