James has been in excellent form for the Lakers as they continue to recover from a desperate start to the season that saw them lose 10 of their first 12 games.
The 38-year-old is averaging 29.1 points per game, along with 8.2 rebounds and 6.7 assists, as the Lakers have improved from 2-10 to 19-21, including winning their last five.
They have averaged 125.8 points per game during that win streak, last winning five in a row while averaging at least 125 points in the 1987-88 season.
After scoring a combined 90 in wins at the Atlanta Hawks (47) and Charlotte Hornets (43), James missed the victory against his former team the Miami Heat on Wednesday with an ankle problem, before returning to score 25 against the Hawks on Friday and 37 against the Sacramento Kings on Saturday.
However, the Lakers listed their star man – the Western Conference Player of the Week – as out again ahead of Monday's clash in Denver, citing left ankle soreness.
James is 20-20 against the Nuggets. He does not have a career losing record against any team.