Robert Lewandowski, Kingsley Coman and Javi Martinez will all miss Bayern Munich's training camp in Doha, which begins on Saturday.
Striker Lewandowski had groin surgery last month and will stay in Germany to continue his recovery, despite having initially planned to be part of the group heading for warm-weather training.
Coman, who has a torn capsule in his left knee, and Martinez, who has a muscle problem, will also miss the trip.
So too does Niklas Sule, who is continuing his recovery from a knee ligament tear sustained in October.
The Bayern squad comprises the available senior players and six youngsters: Joshua Zirkzee, Sarpreet Singh, Leon Dajaku, Oliver Batista-Meier, Chris Richards and Bright Akwo Arrey-Mbi.
The Bundesliga champions will spend a week at the Aspire Academy for Sports Excellence, with interim head coach Hansi Flick promising "an intensive, tough training camp" before they return for a friendly against Nurnberg on July 11.
Their season resumes with a league trip to Hertha Berlin on January 19.