The Brazilian-born Spanish striker was in tears on the sidelines as he was replaced by Adrian after pulling up while unchallenged.
With the Champions League final against Real Madrid in Lisbon just seven days away it looks highly unlikely that he will be available for that clash.
It may also mean he has played his last game for Atletico as he has been heavily linked with a summer move to Chelsea.
Costa has scored 27 goals in La Liga and eight in the Champions League this term.
Things got even worse for Atletico Madrid less than 10 minutes later when Arda Turan was forced off with an injury too with Raul Garcia coming on. The Turk's fitness for the Lisbon final must also now be in serious question.
But at least they had the satisfaction of watching their team-mates win the title on their behalf, as Atletico came from behind to earn the draw they needed to win the title.
- Sports & Recreation
- Atletico Madrid
- Real Madrid
- Arda Turan
- La Liga