The Brazil international has scored twice in seven appearances in cross-city encounters since joining the Reds in January 2013, enjoying two wins and five draws.
He missed the last-gasp victory at Goodison Park in December as he was injured, but is keen to reacquaint himself with the fixture this weekend at Anfield.
"The rivalry is like any derby - it's intense," said Coutinho, who is currently on international duty with Brazil.
"I've experienced these games both home and away and the intensity is equal with the fans.
"You're always on TV, it's one of the most difficult games and I don't think this one will be any different.
"The week before the game, you can't wait to play and if you win, the level of joy you give to the fans is amazing.
"They're the victories you always enjoy."
"It's very important, obviously it's our aim (to finish in the top four)" the 24-year-old said on liverpoolfc.com.
"All the games are like finals and if we're going to achieve our aim we need a lot of points."
Coutinho is in Brazil's squad for a World Cup qualifier at home to Paraguay on Tuesday evening along with club-mate Roberto Firmino.
Liverpool have chartered a private jet to get the pair home as quickly as possible in the hope they can train on Thursday ahead of Saturday's lunchtime kick-off.