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Phil Foden’s missed spot-kick in a last-16 penalty shootout after a goalless draw at West Ham on Wednesday night saw the holders - who have won each of the last four editions - suffer their first defeat in the competition since October 2016.
It was a surprise blip from Pep Guardiola’s City, who had been on a run of three straight wins across all competitions, hitting nine goals in just two matches against Club Brugge and Brighton.
Hoping to avoid an Etihad Stadium backlash this weekend are a 15th-placed Palace side that are making strides under Patrick Vieira, but are struggling to turn decent performances into victories.
The Eagles are on a run of four successive draws in the top-flight, denied wins over rivals Brighton and Arsenal thanks to last-gasp equalisers but showing their own battling qualities to come back from 2-0 down at home to Leicester at the beginning of October.
Date, kick-off time and venue
Manchester City vs Crystal Palace is scheduled for a 3pm BST kick-off today, Saturday October 30, 2021.
The match will take place at the Etihad Stadium in Manchester.
Where to watch Man City vs Crystal Palace
Due to the 3pm blackout rules that were reinstated this season, Saturday’s match will not be broadcast live in the UK.
However, you can catch highlights on Match of the Day on BBC One from 10:30pm.
Man City vs Crystal Palace lineups and team news
Man City: Ederson, Walker, Dias, Laporte, Joao Cancelo, Bernardo Silva, Rodri, De Bruyne, Gabriel Jesus, Foden, Grealish
Subs: Stones, Ake, Sterling, Gundogan, Zinchenko, Steffen, Fernandinho, Mahrez, Palmer
Crystal Palace: Guaita, Ward, Andersen, Guehi, Mitchell, Gallagher, Kouyate, McArthur, Ayew, Edouard, Zaha
Subs: Butland, Milivojevic, Tomkins, Olise, Mateta, Schlupp, Clyne, Benteke, Kelly
Man City vs Crystal Palace prediction
City are unbeaten at home this season and Palace have yet to win on their top-flight travels under Vieira.
In fact, Guardiola’s men have yet to even concede a league goal on their own turf, while the Eagles have shipped 10 on the road.
City will be eager to reimpose their dominance after an unexpected slip-up in midweek, which spells trouble for the visitors on Saturday.
Comfortable home win.
Man City 3-0 Crystal Palace.
Head to head (h2h) history and results
Premier League era
Man City wins: 14
Crystal Palace wins: 3