Ole Gunnar Solskjaer’s side - beaten in the semi-finals of this competition by holders Sevilla last season - go into the second-leg meeting with an enormous advantage having thrashed the Basque outfit 4-0 last week.
Bruno Fernandes starred with a brace in the first-leg thumping that took place in Turin, Italy due to Covid-19-related travel issues, with Marcus Rashford and Daniel James also on the scoresheet.
United followed up that resounding victory with a 3-1 Premier League win over Newcastle on Sunday, while Sociedad bounced back in style with a 4-0 rout of struggling Alaves in LaLiga.
Date, kick-off time and venue
Manchester United vs Real Sociedad is scheduled for an 8pm GMT kick-off today, February 25, 2021.
The contest will be held without fans at Old Trafford due to ongoing coronavirus restrictions.
How to watch Man Utd vs Real Sociedad
TV channel: Tonight’s match will be broadcast live on BT Sport 2 and BT Sport Ultimate, with coverage beginning at 7:15pm.
Live stream: Those with a BT Sport subscription will be able to stream the game live online via the BT Sport website or app.
Man Utd vs Real Sociedad team news
Man Utd XI: Henderson; Wan-Bissaka, Bailly, Lindelof, Telles; Fred, Matic; Greenwood, Bruno Fernandes, James; Martial
Subs: De Gea, Grant, Bishop, Maguire, Rashford, Diallo, Shaw, Williams, Tuanzebe, Galbraith, Shoretire
Man Utd vs Real Sociedad prediction: 2-1 home win
United were rampant at the home of Juventus last week and should have won by more, were it not for some early profligacy in front of goal.
Sociedad have endured a real slide since being top of LaLiga when the last-32 draw was made in December, now sitting fifth and 14 points adrift of leaders Atletico Madrid.
However, they were much improved against an albeit lowly Alaves side on Sunday and head coach Imanol Alguacil, while acknowledging that it will be nearly impossible for his team to go through, has spoken of the need to restore pride at Old Trafford.
They will be going all out to win, though you still fancy United to come out on top once more.
Head to head history (h2h) and results
Man Utd wins: 4
Sociedad wins: 2
Man Utd vs Real Sociedad betting odds and tips (subject to change)
Man Utd to win: 11/10
Sociedad to win: 11/4
Draw: Between 14/5 & 3/1
Man Utd to win 2-1: 17/2
Odds via Betfair Exchange. Click here to find out more.