Man United left the London Stadium on Sunday evening with all three points thanks to a 2-1 win after a gripping finish to the game.
Former West Ham loanee returned to haunt his old club with an 89th-minute strike but the Hammers looked to have been handed a lifeline in the form of Luke Shaw’s late handball.
However, club captain Mark Noble - sent on specifically to take the penalty - saw his spot-kick saved by David de Gea in stoppage time.
Now, just three days later, the sides meet again with a place in the fourth round on the line.
Where to watch Man United vs West Ham
TV channel: The match will be televised on Sky Sports Main Event and Football channels, with kick-off at 7.45pm BST.
Live stream: Sky Sports subscribers can watch the game live via SkyGo.
Live coverage: Standard Sport will bring you all the match action, analysis and reaction.
Read our dedicated match preview here.