March Madness 2017: Second-round betting odds, point spreads for NCAA Tournament

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The highest seeds held serve during the first two days of 2017 NCAA Tournament, but betting underdogs held a slight edge after Thursday and Friday.

'Dogs were 15-14-1(two games closed as pick 'em) as March Madness got into full swing, according to Vegas Insider. Four underdogs won outright: Xavier (+2) vs. Maryland; Northwestern (+2) vs. Vanderbilt; USC (+7.5) vs. SMU; and Michigan State (+2) vs. Miami (Fla.).

A pairof big 'dogs, Mount St. Mary's (+25 vs. Villanova) and South Dakota State (+23.5 vs. Gonzaga), cashed as well. The biggest favorite to cover was North Carolina, which easily handled a 26.5-point spread against 16 seed Texas Southern.

MORE: Point spreads for Friday's games | Printable bracket

With eight more games available for wagering Saturday, business in Las Vegas will again be booming. The Westgate Superbook was offering these lines as of 1 a.m. ET Saturday:

West Virginia -2.5 vs. Notre Dame

Villanova -6 vs. Wisconsin

Florida -2vs. Virginia

Florida State -6.5 vs. Xavier

LIVE UPDATES: SN's NCAA Tournament scoreboard

Butler -3.5 vs. Middle Tennessee

Purdue pick 'emvs. Iowa State

Gonzaga -11vs. Northwestern

Arizona -5 vs. Saint Mary's

And if you want to begin handicapping Sunday's games, a few lines are already out:

North Carolina -8 vs. Arkansas

Louisville -1 vs. Michigan

Baylor -6vs. USC

Oregon -5 vs. Rhode Island

Kansas -8.5 vs. Michigan State

Kentucky -2 vs. Wichita State

Duke -7 vs. South Carolina

UCLA -3 vs. Cincinnati

NOVICK: Why Wisconsin is one of the toughest 8 seeds ever

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