The 31-year-old loose forward has not played since he lifted the Webb Ellis trophy following the All Blacks' victory over France at Eden Park on October 23 last year.
McCaw had battled immense pain throughout the World Cup from a screw that had been inserted to fix a fracture in his foot, which had also kept him out of several weeks of last year's Super Rugby competition.
He had the screw removed after the World Cup and had said he did not expect to play again before April.
The seven-times champions made a slow start to the season, but have started to show signs they will again be strong title contenders after they ended the Stormers' unbeaten run on April 14 then destroyed the Wellington Hurricanes 42-14 last Saturday.
McCaw's All Blacks team-mate Tony Woodcock, however, has been ruled out of Auckland's clash with champions Queensland Reds at Eden Park on Friday after he sustained a calf strain at training.
Woodcock had taken an extended break after the World Cup and made a late start to the Blues' campaign, adding steel to their scrum.
The Blues, tipped as potential champions before the season began, have only won one game in their eight matches and are bottom of the standings on 12 points.
Tevita Mailau moves into the starting line-up to replace Woodcock and Auckland prop Angus Taavao will be the bench replacement.
Blues captain Keven Mealamu is also battling a calf strain and has not been considered for the second successive week with young openside flanker Luke Braid again taking the captaincy.