Miley, who leaves the meet with four medals in total, followed up her win in the 400m medley with another victory in the 200m medley, with British team-mate Sophie Allen taking silver.
Michael Jamieson led home a British 1-2-3 in the 200m breaststroke as James Goddard and Andrew Willis completed the podium.
Georgia Davies won the 50m backstroke while Matt Johnson won the 400m medley, in which Roberto Pavoni took bronze, and rising star Jess Lloyd claimed 100m freestyle silver.
Elsewhere, there were also silver medals for Jemma Lowe in the 200m butterfly, Miley taking third in the same race, and Stacey Tadd in the 100m breaststroke while Jack Burnell placed third in the 1500m freestyle.
Two swimmers who still hope to book their London 2012 selection at this month's ASA Nationals in Sheffield were also among the medals.
David Carry was third over 200m freestyle while Jazmin Carlin took silver in the 400m freestyle.
Rebecca Adlington, who won the 800m freestyle on Saturday, reached the final but admitted she never had any intention of racing again and withdrew.