Munster will face rivals Leinster in the Pro14 semi-finals on Friday after thrashing 13-man Connacht 49-12 on the final day of the regular season.
Connacht had debutant Abraham Papali'i and Shane Delahunt sent off in the first half at the Aviva Stadium on Sunday, making life much easier for Munster as they sealed second place in Conference B ahead of the Scarlets.
Johann van Graan's side were already 14 points to the good courtesy of a Chris Cloete score and a penalty try when Papali'i was dismissed for a dangerous tackle on Conor Murray.
Connacht were two men down when Delahunt was given his marching orders for catching CJ Stander on the neck, and Jeremy Loughman added a third try soon after.
Bundee Aki dotted down on the stroke of half-time to get Connacht on the board after Tadhg Beirne was sent to the sin bin, but Munster ran away with it after the break.
The in-form Andrew Conway grabbed a quickfire double after the impressive Beirne returned to score, and James Cronin also went over the whitewash, with JJ Hanrahan successfully converting five of the seven tries.