What's old is new again in San Francisco, where Jimmy Garoppolo figures to be the starting quarterback the rest of this season after an injury to Trey Lance in Week 2.
They'll face Russell Wilson and the Denver Broncos, who have had a tumultuous first couple weeks but sit at 1-1 and can move above .500 with a win.
Follow all the action with Yahoo Sports right here.
Opera star Ainhoa Arteta has spoken out following protests by locals against UK holidaymakers.
Many people have been left impressed after finding out about the 'little known' function they never knew existed
Stephanie Langley said ‘I’m glad I did it’ as paramedics tried to save him, court told
Samantha Davis, the wife of Star Wars and Harry Potter actor Warwick Davis and herself an actress, has died aged 53. Samantha co-founded the dwarfism charity Little People UK and featured in the final Harry Potter film, alongside Warwick. Warwick announced the news in a statement to the BBC, revealing she had died on 24 March.
Concerns have been raised that people have no idea of a massive post Brexit change which could lead to delays at airports
Following the Cass Review, a riveting ding-dong has broken out on X (formerly Twitter) between JK Rowling and the TV presenter Kirstie Allsopp. In broad terms, Allsopp belongs to the Pollyannaish “Be kind to trans people” (what harm do pronouns do?) side.
Israel’s strike on Iran on Friday morning will not come as a surprise to Western observers – but it will cause great concern in Washington and London as the region tips closer towards an all-out war.
The rock legend appeared live on the show with Ben and Cat Deeley to celebrate and reflect on his 40-year career with his band
The bank has issued a warning to its customers, with the 21 to 40 age group making up nearly half of all reported cases
King Charles is said to have extended an olive branch to his youngest son and his wife by 'hinting' they should visit Balmoral this summer - but it could put the couple in a 'difficult position'.
Meghan Markle was on hand to congratulate her husband Prince Harry and his Royal Salute Sentebale team after they won the Royal Salute Polo Cup in Wellington, Florida
Victoria Beckham marked her 50th birthday on Wednesday and her rarely-seen sister shared a fabulous photo of her Spice Girl sister. See photo.
Robert Oliver left his girlfriend with a head injury after pushing her into a wall in Stockton
BBC Breakfast star Carol Kirkwood has been missing from the show this week. The weather presenter's absence comes after she shared an update on her health last week…
Springtime On The Farm returned to Channel 5 with Helen Skelton and Jules Hudson but fans had the same complaint for the show and the former Blue Peter presenter
The Duke of Sussex has made a change on official documents
The soap star has issued a heartfelt tribute
The conventional wisdom is wrong. We need rational, controlled escalation from the Western powers in the face of Iranian aggression, not more of the sickening appeasement, delusion and cowardice of the past few days. The regime needs to be punished for its monstrous war-mongering, not mollified and placated by a bunch of Western ignoramuses who confuse weakness for virtue.
The dancer confirmed the news to fans ahead of the BBC One dance contest returning later this year
The Lemme co-founder is thankful for her body because it "gave me my 3 big babies and my little baby"
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