Two-time Giro d'Italia winner Vincenzo Nibali has opted to miss the 2018 edition in order to focus his efforts on glory in the Tour de France.
Nibali finished third in this year's Giro, before taking a break from the Tour and returning to take second in the Vuelta a Espana behind Chris Froome.
But it was announced on Thursday that Nibali - one of only six men to win all three Grand Tour general classification titles - will attempt to clinch a second yellow jersey next year, after his maiden triumph in 2014.
"The [Tour] route is quite 'nervous' in comparison with previous editions, much more suited to riders with my characteristics," said Bahrain-Merida's Nibali, in quotes reported by Cycling News.
"It's a route that will suit riders like [Romain] Bardet and [Thibaut] Pinot, it has shorter time trials. It's a more varied route.
"It was always the idea to ride the Giro in my first year with the team and the Tour in my second, but the route has given me extra motivation."
"It hasn't been an easy decision, especially for Vincenzo. The Giro d'Italia goes through his home of Sicily again," added team manager Brent Copeland.
"This programme has been put together between team management, partners and sponsors. It's a project that we've worked on since the beginning and the partners have always asked us to work towards the Giro d'Italia in the first year of the project and the Tour de France in the second year.
"We've respected this and we thank Vincenzo for respecting this. We believe that it is a good Tour de France route."