Coming back from three goals down against Juventus was never going to be an easy task for Barcelona, but having Lionel Messi off his game made the task nearly impossible for the Spanish side on Wednesday.
The Argentine superstar, normally as sure a thing as there is in the world in front of goal, pulled a shot wide in the first half from a good spot and curled another over the bar in the second half with the goal gaping.
With Juve's defense swarming to the ball and closing down space quickly, chances were at a premium, and Barca never found the answer.
For Messi, the day was a particularly rough one as he saw five of his shots miss the target completely.
Only against BATE way back in 2011 did Messi miss the target more times in Champions League play, and with his strike partners Luis Suarez and Neymar both also finding the going tough, the result was predictable.
Messi and Co. must refocus quickly, with the Clasico coming up at the weekend and the side needing a positive result to keep their hopes alive in La Liga.