The duo, who have combined for four of the past eight AL MVP awards, both hit their 28th homer of the season, with Ohtani's coming in the seventh inning to make it a 6-1 game, before Trout finished things off in the ninth frame.
Overall, Ohtani reached base four time just a day after striking out nine batters on the mound, finishing three-for-four at the plate with a walk, while Trout was two-for-five.
They are both tied for ninth in the majors for home runs, although nobody in the top-20 has had fewer at-bats than Trout, who missed over a month of action after suffering an injury in July.
Mookie mashes another moonshot
Betts, who hit two home runs in the opening game of the series on Friday before hitting one more on Saturday, wasted no time on Sunday, smashing the third pitch of the game 416 feet over the center-field wall. His 31 home runs this season tie him for fourth-most in the league.
On the mound, Julio Urias was terrific for the Dodgers, giving up just one hit in six innings, although that hit did go for a home run, and he allowed four walks.
Ray shows his Cy Young credentials
Ray struck out seven batters in seven scoreless innings, conceding just three hits and no walks from 103 pitches.