A 40-year-old man is in hospital with what police are calling serious injuries, following a crash near Ventnor.
Hampshire and Isle of Wight Constabulary said it was called to Whitwell Road at 1.18am this morning.
The collision involved a motorbike and a pedestrian.
The pedestrian, a 40-year-old man from Southampton, suffered serious injuries, police said.
Hampshire and Isle of Wight Air Ambulance airlifted him to Southampton General Hospital for treatment, where he remains.
Anyone with information is urged to contact police on 101 quoting 44230220330.