The Addicks were beaten 4-3 on penalties at The Valley after a fiery London derby finished 1-1 after extra-time.
Powell, who was sent to the stands by the referee an hour into the game, questioned why it had gone ahead before this Saturday's opening Championship game at Birmingham.
"I think it's a crazy decision to be playing a game like this before your first league game and I would say that whether we won or lost," said Powell. "We could have done without it, so could have Orient and a lot of other teams.
"It's a bit of a crazy move that there are internationals and cup games before your league programme, and that goes for all 92 clubs. I'm sure they will have their valid reasons why, but it is just one of those things. I think every club up and down the land should have a clear week going into their first game.
"I'm disappointed we are out, really disappointed because we've seen recently Championship clubs get to the final. Cardiff got there last year and it would have been nice if we'd had a go."
It has been confirmed that Powell will not face a ban as a result of his behaviour.