While the top fixtures this week are no doubt present in the FA Cup, with Tottenham taking on Chelsea and Arsenal challenging Manchester City, most Premier League sides are still in action.
Manchester United make the trip to Burnley on Sunday while Middlesbrough play Bournemouth as they try to avoid relegation.
If you're lagging behind the leader in your fantasy league then there's very little time to address that gap, but who are the players who might help you zoom into the lead?
Eldin Jakupovic - Hull have been strong at home since Marco Silva's appointment and Jakupovic seems the best bet to land you a clean sheet over the weekend with Watford visiting the KCOM Stadium.
Joel Robles - The former Wigan man brought down Sam Vokes to give away a penalty last week and hasn't kept a clean sheet since mid-March.
Phil Jagielka - The England international has scored three goals in his last three games, an unheard of return for Jagielka over his career, but he could pop up with another strike against West Ham.
Erik Pieters - Stoke have been shaky at the back as of late, conceding 10 goals in their last five games, so avoid Pieters when his side travel to Swansea.
Roberto Firmino - The Reds' focal attacking point has been racking up points as of late, scoring the winners against Stoke and West Brom in the last few weeks.
Manuel Lanzini - The Argentine has stepped up to the plate since Dimitri Payet's January move but is without a goal or an assist in his last four games.
Marcus Rashford - The teenager will probably feature up front after Zlatan Ibrahimovic's jarring injury on Thursday and will give Michael Keane and Ben Mee plenty of problems on Sunday.
Andy Carroll - The powerful striker has a groin strain and is likely to miss the Hammers' home tie against Everton.