What is it?
When is it?
It's on Sunday April 23.
What time is kick-off?
This one starts at 7.45pm BST.
What TV channel is it on?
Sky have the rights to La Liga and will be showing this clash on Sky Sports 1 and HD, with coverage beginning at 7pm. Alternatively, you can follow all the action right here with goal updates and analysis.
What is the team news?
Madrid will be without defenders Pepe and Raphael Varane for the game, while Dani Carvajal, Toni Kroos and Gareth Bale all have question marks over their fitness heading into the weekend.
Barcelona will be without Neymar, who was suspended three games after sarcastically applauding an assistant referee in the loss to Malaga in the league two weeks ago. Full team news to be confirmed.
What are they saying?
Real Madrid boss Zinedine Zidane on Cristiano Ronaldo:
"I don't know if there's a category for him. What you see Cristiano doing is really impressive. The goals, the way he finishes them, in such key, important moments," said Zidane of the No. 7.
"He always knows when there's an important occasion, he's going to be there. It is out of any sort of category. There are few players who can to do what Ronaldo has done and we all know that."
Barcelona boss Luis Enrique:
"It will be difficult to lift my players up after this, but it will be easy to motivate them. We have the best stimulus that any Barcelona fan could ask for which is that we play against our eternal rival. There's no better place to go than the Bernabeu.
"We have the chance to get back in the fight for La Liga in a six-pointer against the side top of the league. I love being involved at a club as ambitious as this."
How do things stand in La Liga?
Well, yes. Twitter has unveiled a series of El Clasico-related emojis ahead of Sunday's clash. If that's your kind of thing, you can try them now.
— Daily Mercato (@DailyMercato) April 20, 2017
What are the latest odds?
Real Madrid win: 11/10
Barcelona win: 11/5
What's our prediction?
Barcelona are in a bit of a rut, and without the suspended Neymar, so we expect a narrow win for Real Madrid. And plenty of finger-wagging at the referee.