Real Madrid need only a 1-0 defeat or a draw at the Santiago Bernabeu on Tuesday night to progress to the Champions League semi-finals at the expense of Bayern Munich.
Cristiano Ronaldo's double in the first leg at the Allianz Arena has put Zinedine Zidane's men in firm control of the tie heading into the return fixture in Spain.
And with Madrid having netted two away goals thanks to their talismanic forward, Bayern will need to score at least twice to have any chance of progressing to the last four.
Real Madrid vs Bayern Munich
Tuesday, April 18, 2017
19:45 GMT, 14:45 ET
TV CHANNEL & LIVE STREAM
In the UK, the match will be available to watch live on television on BT Sport 3 and by stream via the BT Sport app.
UK TV channel
BT Sport 3
BT Sport app
In the US, the match will be available to watch live on television on FS1 and by stream via Fox Soccer 2Go.
US TV channel
Fox Soccer 2Go
SQUADS & TEAM NEWS
Real Madrid players
Navas, Casilla, Yanez
Carvajal, Ramos, Nacho, Marcelo, Danilo
Kroos, James, Casemiro, Kovacic, Modric, Asensio, Isco
Ronaldo, Benzema, Vazquez, Morata
Gareth Bale will not be risked after suffering a minor injury in the first leg of the tie. Marco Asensio has tended to replace him, but Isco may be preferred in a position higher up the field after his superb display in the win over Sporting Gijon at the weekend.
Otherwise, Madrid are likely to be unchanged. Pepe and Raphael Varane remain sidelined and Fabio Coentrao has been left out of the squad.
Potential starting XI: Navas; Carvajal, Ramos, Nacho, Marcelo; Modric, Casemiro, Kroos; Bale, Benzema, Ronaldo.
Bayern Munich players
Neuer, Starke, Ulreich
Hummels, Rafinha, Boateng, Bernat, Lahm, Alaba, Kimmich, Feldhahn
Thiago, Ribery, Robben, Costa, Alonso, Vidal, Tillmann, Sanches, Ozturk
Lewandowski, Muller, Coman
Bayern could have a problem at centre-back, where Mats Hummels and Jerome Boateng both face late fitness tests and 30-year-old Bayern II player Nicolas Feldhahn has travelled as emergency cover.
Robert Lewandowski is definitely fit, however, after missing the first leg with a shoulder injury. He is likely to directly replace the out-of-sorts Thomas Muller.
Potential starting XI: Neuer; Lahm, Hummels, Boateng, Alaba; Thiago, Alonso, Vidal; Robben, Lewandowski, Ribery.
BETTING & GAME ODDS
Real Madrid are 7/5 favourites to win on the night, according to Oddschecker. The draw can be backed at 3/1 and Bayern Munich are priced at 19/10.
Cristiano Ronaldo is the 15/4 favourite to score first, with Robert Lewandowski next at 9/2 and both Karim Benzema and Alvaro Morata available at 13/2.
At the Santiago Bernabeu, we will finally find out what kind of Bayern Munich team Carlo Ancelotti has created in his first season at the helm.
The combination of the Italian, a European specialist, and an immensely talented Bayern squad hungry to add another Champions League title to their collection of Bundesliga trophies seemed a perfect fit.
After finishing behind Atletico Madrid in the group, it seemed Bayern were turning it on when it mattered when they smashed Arsenal 10-2 on aggregate in the last 16.
The Gunners have been a mess for the past couple of months, though, losing to plenty of teams other than the Germans, and lost their best central defender - Laurent Koscielny - in both legs, first to an injury and then to a red card.
Then came Real Madrid and a surprise 2-1 defeat at home, but that was without Robert Lewandowski and Mats Hummels, two of the most integral members of Ancelotti's lineup.
They are both expected to be back for the return fixture in Spain and we will finally find out if this Bayern team is still capable of big results or in need of regeneration, with Philipp Lahm and Xabi Alonso playing their final campaigns.
Even their best, though, might not be enough against a Madrid side that has shown steel and character to go with their talent under Zinedine Zidane.