The Packers quarterback has been banged up throughout this season, nursing a right thumb injury along with sore ribs, picking up a left knee issue in Sunday's 26-20 win over the Miami Dolphins.
That victory, the Packers' third straight win, kept their playoffs hopes alive with a 7-8 record in the NFC North, but losing to the division-leading Vikings will all but put an end to that, with Rodgers' availability likely to be pivotal.
"I got a lot of body weight on my knee," Rodgers told reporters about the injury sustained when defensive tackle Christian Wilkins fell on him.
"Had some extra flexion I haven't known for the last 20 years. So just been doing rehab the last few days and feeling a lot better."
Rodgers did play out Sunday's win but said fluid began to build on his knee during the flight home from Florida to Wisconsin.
The 39-year-old four-time MVP, who hoped to practice on Thursday, said these issues were part and parcel of the NFL.
"You're dealing with something throughout the year whether it's a major or minor, always got to do the body maintenance," Rodgers said.
"But it's a good opportunity for [backup QB Jordan Love] to practice and get his reps in, and it's a good opportunity for me to get some rest."
The Packers would be eliminated from playoffs contention if they lose to the Vikings, and one of the Detroit Lions (7-8) or the Washington Commanders (7-7-1) win their Week 17 games against the Chicago Bears and the Cleveland Browns respectively.