A club viewed as potential top-four contenders before the season started have plummeted to 10th following defeats to Exeter, Bath, Wasps and Harlequins.
Leicester arrive at Kingsholm hoping to climb back into the top four, but Davies insists Gloucester are fired up by what they view as a key fixture .
"It's always a huge game in its own right, but it's particularly important for us at this stage where we're desperate for a win," Davies said.
"We've not performed anywhere near the levels we expect of ourselves and we need this win. It's a crucial fixture for us.
"Leicester come here with a physical edge and look to squeeze us at the set piece. That's what they do week in, week out.
"We need a big performance, we need a result and it's going to be a huge game for us."
England prospect Henry Trinder returns from a quad strain at outside centre, one of five changes made by Gloucester.
Leicester are hoping to climb back into play-off places but centre Matt Smith, who is struggling with a hamstring problem, is the latest player to be added to a list of casualties that already includes Manu Tuilagi, Anthony Allen and Geoff Parling.
A 20-11 victory over London Irish last Saturday ended a two-match losing league run against Wasps and Harlequins and director of rugby Richard Cockerill believes sixth-placed Leicester have steadied the ship.
"We battled through the game against London Irish to take the points, though we can play a lot better," Cockerill said.
"We needed that win after a couple of disappointing results, but the squad will be better for it and we know we need to push on from here."
- Sports & Recreation