The Treviso player excelled in the Celtic League last term and replaces fellow Argentina-born Luciano Orquera, who drops to the bench having been the main fly-half during Italy's strong Six Nations campaign in February and March when they beat France and Ireland.
Edoardo Gori continues at scrumhalf as he looks to make the spot his own in a mini-series also involving Samoa and Scotland.
Lock and former captain Marco Bortolami returns to the line-up after a year out following a shoulder injury.
15-Andrea Masi, 14-Giovanbattista Venditti, 13-Luca Morisi, 12-Alberto Sgarbi, 11-Luke Mclean, 10-Alberto Di Bernardo, 9-Edoardo Gori, 8-Sergio Parisse, 7-Robert Barbieri, 6-Alessandro Zanni, 5-Marco Bortolami, 4-Antonio Pavanello, 3-Lorenzo Cittadini, 2-Leonardo Ghiraldini, 1-Alberto De Marchi
16-Davide Giazzon, 17-Matias Aguero, 18-Martin Castrogiovanni, 19-Valerio Bernabo, 20-Joshua Furno, 21-Tobias Botes, 22-Luciano Orquera, 23-Tommaso Iannone.
- Sports & Recreation
- Luciano Orquera
- Marco Bortolami