The sixth-placed Chiefs head up for an appointment with their title play-off rivals, who are one point and one spot above them. Exeter gained a thrilling victory in last season's corresponding Aviva Premiership fixture at Kingsholm and they will arrive this time around following home and away victories over Heineken Cup opponents the Scarlets.
"Momentum is important," Exeter flanker Scaysbrook said. "We have had two big victories over the last two weeks and it has really lifted the squad. The Scarlets are a top-quality team with a lot of experienced internationals and we couldn't ask for much more moving forward."
He added: "Our focus over the last two weeks has just been to put in two really good performances and maintain our momentum.
"It is important to keep the momentum going through the different competitions. We have some tough games over Christmas and the next few weeks, so we will do all we can to maintain that form. We have had some tough battles with Gloucester over the years, and I think this weekend will be no different."
Premiership leaders Harlequins take on third-placed Northampton at Franklin's Gardens on Saturday, while Saracens visit Bath and struggling London Irish host Leicester. Worcester boss Richard Hill believes it will take a "top-notch" effort from his players to keep Premiership newcomers London Welsh at bay on Friday night.
Worcester's Sixways opponents have already won four games this term - one more than the ninth-placed Warriors - and are 13 points clear of bottom club and relegation favourites Sale Sharks, who travel to Wasps on Sunday.
"London Welsh have had a very good season and cannot be underestimated," Hill said. "Most people wrote them off before the season started so it is credit to the coaching staff and players that they have played with no fear and have got their tactics right against most teams."
Captain and lock James Percival returns to the Worcester starting line-up as one of four changes from last weekend's 13-6 Amlin Challenge Cup defeat in Perpignan. Wing David Lemi is recalled, while full-back Chris Pennell and centre Josh Matavesi also feature as Worcester look to extend an unbeaten home record stretching back until early September.
London Welsh head coach Lyn Jones has named a side showing 13 changes after last weekend's Challenge Cup home loss to Grenoble, with only full-back Tom Arscott and centre Seb Jewell retained.
- Sports & Recreation