Saracens vs Harlequins, Aviva Premiership: live score updates

• Kick-off at 15:00 GMT

• Third-placed Saracens now 12 points behind leaders Exeter

3:04PM

PENALTY LOZOWSKI! Saracens 3-0 Harlequins

Easy as that, as Saracens take the lead.

3:04PM

2 mins - Saracens 0-0 Harlequins

Robshaw pinged at the breakdown for going off his feet, giving Lozowski a chance to open the scoring. Robshaw a little unlucky, just slipped going for the ball.

3:02PM

Kick-off

Saracens with the honours, Care clearing with a box kick through the smoke left by the fireworks. Saracens starting an attack inside Harlequins' half, playing in blue today.

3:01PM

Monye's hidden talent

Who knew he could smash over drop goals like this?

3:00PM

Out come the teams

2:44PM

Saracens boss Mark McCall on Maro Itoje's form and fitness

"Maro's last game for us was against Northampton in the European Cup. He has had a lot of rugby in the last couple of years and we have to plan for that."

Billy Vunipola meanwhile is uncertain for next weekend's game European quarter-final against Leinster.

2:41PM

The run-in for Saracens

Five games to go, all winnable you would have to think, as they battle with Wasps for second place behind Exeter.

2:38PM

Two England nines against each other

Wigglesworth and Care have been vying a starting spot with England for most of the Six Nations, and now they go up against each other. Wigglesworth has already confirmed to BT Sport that there will be post-match beers.

2:22PM

Wray the West Ham fan

And Charlie Morgan this week also spoke to Saracens back-row Jackson Wray, a West Ham supporter playing today at his favourite club's new home. Wray was also a spectator during the defeat to Burnley which saw notable crowd trouble.

2:18PM

Eyes on Chisholm

Our very own Charlie Morgan has picked out the Harlequins back-row James Chisholm as a player to watch following the NatWest Six Nations.

2:01PM

Welcome

Afternoon everyone. Lots of talk this week about fatigue among England's players but there are several in action today, including Saracens star Maro Itoje.

He joins Richard Wigglesworth (Saracens), Mike Brown, Danny Care, Chris Robshaw and Kyle Sinckler (all Harlequins) who all start at the London Stadium, current home of West Ham and previously the venue for the 2012 Olympics.

Mako Vunipola (Saracens) and Joe Marler (Harlequins) gets starts off the bench for their respective sides while Saracens have also welcomed back Liam Williams from Wales duty.

Some quick match facts courtesy of Stuart Farmer Media Services:

• London Stadium becomes Premiership Rugby’s 37th venue and the seventh different home venue for Saracens in the tournament.

• Saracens have lost their last two matches, at home to Leicester and away at Exeter, and have not lost back-to-back home games in Premiership Rugby in the same season since they were at Vicarage Road in 2005/06.

• Harlequins 20-5 win at home to Bath in round 17 ended a four game losing run in Aviva Premiership Rugby.

• Harlequins only away victory in the tournament this season was against Wasps at Ricoh Arena in Round 3.

• The last six fixtures between the two clubs in Premiership Rugby have been evenly split with three wins apiece.

Teams as follows:

Saracens: 15 Alex Goode, 14 Liam Williams, 13 Marcelo Bosch, 12 Brad Barritt, 11 Sean Maitland, 10 Alex Lozowski, 9 Richard Wigglesworth; 1 Richard Barrington, 2 Jamie George, 3 Juan Figallo, 4 Maro Itoje, 5 Dominic Day, 6 Nick Isiekwe, 7 Schalk Burger, 8 Jackson Wray,
Replacements: 16 Schalk Brits, 17 Mako Vunipola, 18 Titi Lamositele, 19 Ben Earl, 20 Blair Cowan, 21 Ben Spencer, 22 Max Malins, 23 Chris Wyles

Harlequins: 15 Mike Brown, 14 Alofa Alofa, 13 Joe Marchant, 12 Jamie Roberts, 11 Tim Visser, 10 Demetri Catrakilis, 9 Danny Care; 1 Mark Lambert, 2 Joe Gray, 3 Kyle Sinckler, 4 Charlie Matthews, 5 James Horwill (c), 6 Chris Robshaw, 7 Luke Wallace, 8 James Chisholm
Replacements: 16 Dave Ward, 17 Joe Marler, 18 Will Collier, 19 Mat Luamanu, 20 Jack Clifford, 21 Dave Lewis, 22 Marcus Smith, 23 Francis Saili