The Hoops midfielder has been battling all season with a hip complaint, only playing intermittently and usually in the big games, but had to succumb to the pain in the second half when he was replaced by Kris Commons.
Parkhead boss Lennon said: "Scott Brown has run his course, we may have to book him in for surgery. We are looking at eight to 10 weeks."
He added: "He has been pushing himself to the limit and we can't keep asking him to put himself through the amount of distress that obviously he was doing towards the end of his time on the pitch.
"He has been a huge player for us this season, I think it is time to get the problem addressed and hopefully he will have something to look forward to in the new year."
Lennon was alluding to the fact that Celtic's bid to win through to the knockout stages of the Champions League will go to their last Group G fixture.
Ola John gave the home side the lead in the seventh minute before Georgios Samaras levelled in the 32nd minute from a Charlie Mulgrew corner. Defender Ezequiel Garay restored Benfica's lead in the 72nd minute to ultimately, and deservedly, leave both sides on seven points after five games.
The Scottish champions, guaranteed a Europa League spot after Barcelona beat Spartak 3-0 in Moscow earlier in the evening, will go through if, in their home game against the Russian club, they better the Portuguese side's result in Barcelona.
Lennon admits his last-16 hopes are in the balance, as he said: "I think Benfica are capable of getting a win in Barcelona, for they are an excellent side. But we have to make them do that.
"I don't know what kind of mindset Spartak will be in, they might want to spoil our party, we have to be totally focused. What we have to do is win at home and make Benfica win in the Nou Camp which is no easy feat. The onus is on us to do that."
- Sports & Recreation