Both teams still have an eye on Europe, but with teams around and above them performing well, three points tonight are a must.
The Blades have won just one of their five games since the restart and are down to ninth place.
Wolves were doing well with three straight wins, but then lost to Arsenal last time out.
Here’s everything you need to know about the game.
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When is it and what time is kick-off?
The match will begin at 6pm on Wednesday 8 July at Bramall Lane.
How can I watch it online and on TV?
The game will be broadcast live on Sky Sports Main Event and Sky Sports Premier League, plus Sky Sports Ultra HD.
Sky Sports subscribers can also stream the game on the Sky Go app. If you’re not a Sky customer, you can grab a NOWTV Day Pass here to watch without a subscription.
Sheffield United: Henderson, Baldock, Stevens, O'Connell, Basham, McBurnie, Sharp, Egan, Norwood, Osborn, Berge.
Wolves: Patricio, Boly, Coady, Saiss, Doherty, Otto, Moutinho, Neves; Adama, Jota, Jimenez.
What are the odds?
Sheffield United – 16/5
Draw – 11/5
Wolves – 6/5