Chris Wilder’s side have fallen agonisingly short of a place in next season’s Europa League, with sixth-place Wolves now out of reach.
However, that can hardly detract from a fabulous first season in the top flight for the Blades, who’ve defied expectations since the very start.
Southampton have been in terrific form since the restart, after Ralph Hasenhuttl completed a remarkable reversal of fortunes, with the Saints now undefeated in their last six games.
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When is it and what time is kick-off?
The match will begin at 4pm on Sunday 26 July at St Mary’s.
How can I watch it online and on TV?
The match will be broadcast live on Sky Sports Mix.
If you’re not a Sky customer you can grab a NOWTV Day Pass here to watch without a subscription.
Southampton: McCarthy; Walker-Peters, Stephens, Vestergaard, Bertrand; Armstrong, Ward-Prowse, Romeu, Redmond; Ings, Adams.
Sheffield United: Henderson; Basham, Egan, Robinson; Baldock, Berge, Lundstram, Fleck, Stevens; McBurnie, Sharp.
What are the odds?
Southampton – 23/20
Draw – 5/2
Sheffield United – 23/10