Herbert played through apparent pain in Thursday's 27-24 loss to the Kansas City Chiefs following a series of big tackles on the QB in the fourth quarter.
The Chargers QB still managed to find DeAndre Carter and then Josh Palmer in an impressive drive for a late touchdown but seemed in discomfort and gestured towards his ribs on the sidelines.
Herbert did not appear for post-game media duties, instead going off for an X-ray on the injury, although Staley was confident he would be fine.
"No," Staley told reporters when asked if he was concerned about Herbert's health. "No, because he's Justin Herbert."
Staley added: "You're not going to see a quarterback at any level of football play tougher and do more for their team and will their team to give them a chance more than him.
"There's nobody that can do what he can do, nobody. He showed a lot of guts, he showed us what he shows every day, that we're never out of the fight, and he brought us back and gave us a chance."
Despite that, Staley revealed they anticipate they will learn more about Herbert's health on Friday after a more thorough evaluation.
"I think that we're going to learn a lot more tomorrow," he said.
"It was just a tough NFL game and he took some big hits and none of those big hits had any impact on him bringing his team back like he always does."