Hull's biggest win of the season reinforced their play-off credentials and sent a message to the top four they may have extra competition this year in the form of Peter Gentle's side.
Tickle also added nine conversions and Hull's further tries were scored by Willie Manu (2), Andy Lynch, Richard Whiting, Sam Moa and Tom Briscoe.
Paddy Flynn scored two tries - one converted by Gareth O'Brien - within the closing 10 minutes for the Vikings, but it was too little too late for the Dennis Betts' side.
The Vikings have now conceded 310 points already this season and with only seven games played, that is an alarming figure for the basement strugglers.
The Warriors reverted to a full-strength side after a weakened team suffered a shock 37-36 defeat at Widnes last week, and they made a sluggish start. The Warriors then kept their noses in front during the second half, finishing with seven tries to five, with scrum-half Brett Finch scoring in each half.
Pat Richards also had one try and seven goals to move to the brink of the 2,000-point mark for Wigan with Gareth Hock, Darrell Goulding, George Carmont and Sam Tomkins also crossing over for the Warriors.
London stand-off Michael Witt made all five kicks to go with his two tries to finish with 18 points for the visitors, while Michael Robertson, Daniel Sarginson and Chris Melling also got a try apiece for the Broncos.
The Wildcats turned in a battling performance and would have gone away with a draw had Isaac John been able to convert Vince Mellars try six minutes from time.
Richie Myler scored two tries for the Wolves, with additions from Ryan Atkins, Ben Westwood, Simon Grix and Joel Monaghan - Lee Briers was successful with three goals.
While, Danny Washbrook, John, Richie Mathers, Ali Lauitiiti and Mellars crossed over for the Wildcats, with John adding five conversions for Richard Agar's men.
It was a gutsy effort by the Cats who have now lost five matches in a row since their win at Widnes on the opening day of the season.