The draw took place on Thursday and Tottenham are alongside Eintracht Frankfurt, Sporting Lisbon and Marseille in Group D.
While they avoided some of Europe's biggest clubs, Spurs manager Antonio Conte was not willing to underestimate any of their opponents.
"We're talking about the most important and difficult competition in Europe, maybe in the world because you find the best teams in the world in this competition," Conte insisted.
"I think the draw and our group, I see balance. For sure our target is to try to go to the next round, this has to be clear.
"I think we gained the possibility to play this important competition and we want to enjoy, to play good football and have the possibility to go far."
Tottenham Champions League fixtures and kick-off times
September 7, 2022: Tottenham vs Marseille, 8pm
September 13, 2022: Sporting vs Tottenham, 5.45pm
October 4, 2022: Eintracht Frankfurt vs Tottenham, 8pm
October 12, 2022: Tottenham vs Eintracht Frankfurt, 8pm
October 26 2022: Tottenham vs Sporting, 8m
November 1, 2022: Marseille vs Tottenham, 8pm