Medvedev will lose the world number one ranking after the four-set defeat while Kyrgios moves on to a last-eight clash with Karen Khachanov.
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Kyrgios is no stranger to self sabotage but this was a particularly ridiculous way to lose a point. By hitting a shot on Medvedev’s side of the net, even though the ball had not gone over the net, Kyrgios forfeited what would have been a break point.
Corentin Moutet getting ready for a fourth set against Casper Ruud (probably).pic.twitter.com/0NUyRZ4vjJ
— US Open Tennis (@usopen) September 4, 2022
Women: Alison Riske-Amritraj (29), Veronika Kudermetova (18)Men: Daniil Medvedev (1), Pablo Carreno Busta (12)
Who’s up next?
— LTA (@the_LTA) September 4, 2022
Cameron Norrie takes on Andrey Rublev in the first match on Louis Armstrong Stadium on Monday as he bids to reach a second successive grand slam quarter-final.
Rafael Nadal faces American favourite Frances Tiafoe on Arthur Ashe while Carlos Alcaraz, who remains in contention to take over as world number one, meets former champion Marin Cilic.
Iga Swiatek, who is looking to make her first US Open quarter-final, plays German Jule Niemeier.