After a close opening quarter the Spanish side began to pull clear, but more through their impregnable defence than through their creative flair in attack.
The Germans were restricted to just 22 points in the first half, with Matt Nielsen winning the MVP award after collecting six rebounds. Kosta Perovic led the champions' attack with 17 points, while Thomas Kelati scored 13 from the bench.
"I think we played almost a perfect defensive game," said Valencia coach Neven Spahija, after his team restricted Berlin to a record low tally in a finals match just 24 hours after the same players set a record high score of 92 points in their semi-final.
"We have shown here that we can win with defense or with offense. But tonight, we needed to do it with defense, and we did. I am very happy for everyone!"
In the third-fourth place play-off, local favourites Bilbao beat Panellinios 76-67.