The Hammers are bidding to win a first major trophy since the FA Cup in 1980. Here, Planet Sport looks back at their route to the final.
West Ham's journey to Prague began on August 18, three Prime Ministers ago, with a home meeting against Danish minnows Viborg.
New Italian striker Gianluca Scamacca, Jarrod Bowen and Michail Antonio scored in a 3-1 first-leg win. Scamacca was on target again, along with Said Benrahma and Tomas Soucek, in the away leg to secure a comprehensive 6-1 aggregate victory.
They fell behind to FCSB at home in their first match but goals from Bowen, Emerson Palmieri and Antonio earned a 3-1 win and David Moyes' side went on to breeze into the knockout stages with six wins out of six.
The travelling fans were rewarded with a trip to sunny Cyprus and a tie against AEK Larnaca.
West Ham were struggling domestically, having just been knocked out of the FA Cup by Manchester United and thumped 4-0 at Brighton in the Premier League, but Antonio's double settled the away leg and a brace from Bowen helped them to a 4-0 win at home, and 6-0 on aggregate, to keep the European adventure going.
Next up were another Belgian outfit, Gent, and for the first time in the competition West Ham failed to register a victory, with Danny Ings on target in a 1-1 away draw.
Dutch dark horses AZ Alkmaar would be no pushovers in the last four having already accounted for Lazio and Anderlecht.
West Ham fell behind at the London Stadium to Tijani Reijnders' first-half goal but Said Benrahma's penalty and Antonio's scrambled effort secured a 2-1 win.
In an edgy second leg, Pablo Fornals raced through to score the only goal in stoppage time to inflict AZ's first European defeat in 26 matches and send the Hammers through.
The article West Ham United's route to the Europe Conference League final against Fiorentina appeared first on Planetsport.com.