Powell was speaking before her side opens their 2013 European Championship campaign against Spain in Sweden on Friday evening (7.30pm kick-off).
Powell played for England between 1983 and 1998 winning 66 caps and scoring 35 goals.
The national coach said: "I think physically the guys are obviously a lot stronger than the women..but if we took it on technical ability we're as good as the men. We'd give it a good go.
"Women's football is sometimes considered secondary, but the growth of the game means more people are interested in the game and it's flourishing."
Much like the men, England toil against the Germans in the women's game.
England were unbeaten in qualifying for the tournament and aim to go one better having lost 6-2 to Germany in the 2009 final.
Powell's side go into the tournament on 11-match unbeaten run in competitive games, but is aware of the benefits of glory in Sweden with the possibility of professionalism on the horizon.
"It would mean all the good work over the years would all be worth it," said Powell. "Hopefully we could get more investment and the game would be professionalised sooner rather than later.
Powell added: "We had a UEFA study visit where we went to Germany; we try and look at what everyone else in the world is doing.
"We have to remember that Germany have a larger pool of players to choose from and that helps them massively. Germany women 20-25 years ago were in the same position as we are. It takes time but the FA are investing more and we are heading in the right direction.
"It's important to recognise we have our own culture and our own DNA, it's important to work with that, but we will continue to strive to become the leading nation in women's football."
- Sports & Recreation